JRE MMA Show #186 with Sean Sharaf · Aired Oct 1, 2026
Claim summary · not a verbatim quotation
Studies show that creatine basically mitigates all the negative effects of sleep deprivation on mental performance.
The finding
What the evidence shows
The main study behind this, Gordji-Nejad and colleagues in Scientific Reports (2024), gave 15 young adults one very large dose of creatine, about 25 grams, during a night without sleep. It improved memory and processing speed compared with a placebo. The authors say it only partly reversed the decline from lost sleep and did not restore normal performance, and they warned against taking such high doses at home. It helped, but it did not erase the effects.
Read the supporting source · pmc.ncbi.nlm.nih.gov ↗Quick answer & review status
Quick answer
Is it true that studies show that creatine basically mitigates all the negative effects of sleep deprivation on mental performance?
Partly. The claim stretches what the evidence shows. The main study behind this, Gordji-Nejad and colleagues in Scientific Reports (2024), gave 15 young adults one very large dose of creatine, about 25 grams, during a night without sleep. It improved memory and processing speed compared with a placebo. Joe Rogan said it (matched by voice) on JRE MMA Show #186 with Sean Sharaf, aired Oct 1, 2026, at 1:05:43. The supporting source is pmc.ncbi.nlm.nih.gov, linked below.
The context belongs here.
No separately verified on-air correction is recorded for this check. That is not a claim that nobody corrected it.
- Attribution
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- Editorial context review
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- Coverage
- One selected claim from the episode
Revisions to this check
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