Joe Rogan Experience #2544 - Chris Williamson · Aired Aug 21, 2026
Claim summary · not a verbatim quotation
About 90% of people who use GLP-1 drugs for weight loss gain the weight back after discontinuing their use.
The finding
What the evidence shows
The direction is right, the number is not. In the STEP 1 trial extension, people who stopped semaglutide regained about two thirds of the weight they had lost within a year, and were still down about 5.6% from where they started. That is a lot of regain, but it is not 90% of people getting all of it back.
Read the supporting source · pmc.ncbi.nlm.nih.gov ↗Quick answer & review status
Quick answer
Is it true that about 90% of people who use GLP-1 drugs for weight loss gain the weight back after discontinuing their use?
Partly. The claim stretches what the evidence shows. The direction is right, the number is not. 6% from where they started. Chris Williamson said it (matched by voice) on Joe Rogan Experience #2544 - Chris Williamson, aired Aug 21, 2026, at 1:52:52. The supporting source is pmc.ncbi.nlm.nih.gov, linked below.
The context belongs here.
No separately verified on-air correction is recorded for this check. That is not a claim that nobody corrected it.
- Attribution
- Not independently confirmed in this record
- Editorial context review
- Not recorded; generated finding
- Coverage
- One selected claim from the episode
Revisions to this check
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